Depression and heart-disease drugs are to be tested in a trial to find treatments for multiple sclerosis (MS) from existing medicines.
There are currently no treatments in the secondary progressive stage of the debilitating disease.
Doctors hope the necessary drugs are already out there, but have never been tested on MS.
More than 400 people will take part in the trial at University College London and the University of Edinburgh.
Walking, balance, speech, and vision become impaired in the later stages of the disease.
There are treatments in the early phases of MS to prevent the frequency or severity of relapses. But there is nothing once the disease progresses.
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