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Less affluent female cystic fibrosis sufferers 'continue to die younger'

Females and individuals from socioeconomically disadvantaged backgrounds with cystic fibrosis continue to die younger than males and the more privileged in society, a study says.

The British Medical Journal's (BMJ) findings suggest that the socioeconomic and sex differences in age at death from cystic fibrosis first reported in 1989 persist to the present day.

Over the last 50 years, survival in individuals with cystic fibrosis has

improved dramatically with the average age of death rising from six months

in 1959 to 27 years in 2008, largely due to better health care provision.

Around 20 years ago, it was shown that age at death was higher among men

and those from socioeconomically advantaged backgrounds. But is this still the case?

A team of researchers based at the University of Nottingham decided to test

the theory that improved healthcare provision has led to a decline in these

socioeconomic and sex differences. They analysed all registered deaths from

cystic fibrosis in England and Wales from 1959 to 2008.

Between 1959 and 2008, the median age at death increased from age band 0-4 years to age band 25-29 years, and from the mid 1970s onwards tended to be higher in males than females.

After adjusting for socioeconomic status, males were more likely to die

above the median age than females in the 1970s and 1980s. Median age at

death was also significantly higher in males compared with females between

2000 and 2008.

Between 1959 and 2000, median age at death was higher in the 'non-manual'

occupation group compared with the 'manual' group. Between 2001 and 2008,

median age at death also tended to be higher in the 'professional and

managerial' group compared with the 'routine and manual' group.

"Healthcare workers should be aware that females and low socioeconomic

status are associated with poorer outcomes than males and high

socioeconomic status," said the authors of the BMJ report. They suggest that

environmental factors or varying access to healthcare might account for

some of these differences.